Join Lonza's experts during the podium and workshop presentations. Schedule a meeting to discuss your next project with our representatives at the event. 

Respiratory Drug Delivery (RDD) 2021 is the must-attend, premier international conference for researchers, regulators, business professionals, and suppliers active in pulmonary and nasal drug delivery. Learn more about the event here.
 
 
We hope you can join us for the following virtual presentations. Mark your calendar!
  
 

Podium presentation

 

Kim

Pulmonary delivery of monoclonal antibody spray-dried dispersions

Available on-demand on the RDD Conference platform from 27th April 2021. 
For the Q&A session meet the speaker at the session - Explore with Experts - Thursday, 6 May 2021. 4 PM CEST.
 
 
Locally administered biologics are of great interest for treatment of lung diseases, but development of shelf-stable, dry-powder formulations for inhalation has remained a challenge. This work describes manufacture of a monoclonal antibody (mAb) as a stable, respirable, biologically active pulmonary formulation using spray drying. This case study was focused on bevacizumab, which is approved for treatment of non-small-cell lung cancer (NSCLC) by intravenous (IV) infusion. A bevacizumab spray-dried dispersion (SDD) was successfully prepared. Using in vivo tests with an orthotopic nude rat model, the inhaled bevacizumab SDD was shown to reduce NSCLC tumor burden at one-tenth the dose used for the injected bevacizumab control formulation.

  

Workshop presentation

immy Beaty

Cameron Kadleck

Cameron Kadleck, Respiratory Scientist, Product Development

Biorelevant aerosol testing and modeling for respiratory drug delivery

 
Available on-demand on the RDD Conference platform from 27th April 2021.
For the Q&A session meet the speakers at the session - Conversations with Workshop Presenters - Thursday, 6 May 2021. 5:15 PM CEST.
 
Participants in this workshop will be provided with an overview of the differences in approach for jet milling and spray drying particle engineering. They will learn what types of questions can be answered using bio-relevant aerosol testing. Additionally, participants will understand how the selection of parameters for sensitivity analysis in respiratory drug delivery modeling can provide insights into the in vivo fate of inhaled therapies.
 
  
 

Meet 1-2-1 with our expert in the virtual event: schedule a session.

 

 
Can’t attend the virtual event? Access other relevant technical content in our Knowledge Center:
  • On-demand webinar "Local Delivery for Treatment of Lung Cancer: Manufacturing formulations for dry powder inhaler by spray drying", watch now
  • Whitepaper/Executive summary "Particle Engineering For Inhalation Drug Delivery", read now
  • Article "Particle Engineering for Dry Powder Inhalers", read now
   



  
 

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