Your complete LAL‑to‑rFC transition toolkit—one form, five practical resources
Get a decision-tree validation guide, a proven rapid protocol for high-throughput QC, and platform resources that support confident adoption of rFC.
If you’re evaluating a move from traditional LAL to recombinant Factor C (rFC), this resource bundle is designed to help you move from questions to clarity: what to validate, how to streamline implementation, and how to select the right reader and workflow support to maintain confidence and continuity. Here is what you will receive when you complete the form:
- PyroGene® rFC Assay validation considerations: This technical tip outlines key validation considerations for implementing the rFC assay for raw materials, in‑process samples, and final product. It includes a practical decision tree and clarifies when “validation of an alternative method” is needed.
- Optimized rFC protocol for rapid endotoxin testing in high-throughput QC laboratories: See how the PyroGene® rFC Endpoint Fluorescent Assay can be adapted to a 20‑minute incubation protocol while maintaining reliable detection at 0.1 EU/mL—validated across multiple reagent lots and Nebula® Multimode Readers.
- Nebula® Reader Business Continuity: If you’re planning around the discontinuation of sales of the ELx808™ Microplate Reader, this resource summarizes why the Nebula® Absorbance Reader is positioned as an ideal replacement for quantitative endotoxin detection absorbance assays.
- PyroGene® Recombinant Factor C Assay overview: A high-level brochure describing rFC as the evolution of traditional LAL—highlighting that PyroGene® rFC is not derived from horseshoe crab blood, works via a single enzymatic step, and is designed to be endotoxin-specific (avoiding false-positive glucan reactions).
- Nebula® Multimode Reader: A concise overview of the 96 well reader that combines absorbance and fluorescence in a single footprint—supporting traditional LAL assays and recombinant technology (including PyroGene® rFC).
Submit the form once to unlock all resources on this page—instant access in one place.

