UC-II Sourcing and Sustainability

UC-II^® undenatured type II collagen

Sourcing and sustainability

At Lonza, sustainability is a key consideration in everything we do.

As the proud manufacturers of UC-II^® undenatured type II collagen, the number one undenatured type II collagen brand globally,^* we prioritize responsible sourcing and sustainability practices in every step of our journey.

Watch the video to learn more

From farm to facility

UC-II^® is a premium ingredient derived from chicken cartilage sourced in the United States. Its production plays an important role in supporting a circular economy – a system designed to reduce waste and promote a more sustainable use of natural resources. The video takes you on a journey from Lonza-qualified suppliers to USDA-inspected facilities, emphasizing our commitment to quality and animal welfare.

Responsible sourcing

Lonza Capsules & Health Ingredients is committed to upholding the highest social, environmental, and governance standards in our journey toward enabling a healthier world. Our Supplier Code of Conduct sets the stage for responsible sourcing, ensuring strict compliance standards are met by suppliers. Learn about our rigorous audit process, underlining our commitment to sustainability in every step of the supply chain.

Operational excellence

UC-II^® is produced using a patented manufactured in a state-of-the-art facility in the United States that meets strict safety requirements and has programs in place to ensure animal welfare. Learn more about our commitment to ensuring the quality and purity of UC-II^®.

To learn more, watch our video on UC-II^® sourcing and sustainability

As the #1 undenatured type II collagen brand on the market*, UC-II^® meets consumer demand for an easy-to-use, efficacious joint health supplement in the competitive active lifestyle category.

Clinically proven

The most researched brand of undenatured type II collagen with clinically proven benefits for joint health and mobility.

Low dose

Unsurpassed consumer convenience with proven benefits in only one small 40 mg dose per day.^1,2

Unique mechanism of action

Patented manufacturing process maintains the unique mode of action, signaling the immune system to build new cartilage.^3,4

Formulation-friendly

Works across a wide range of applications, and small dose makes it perfect for all-in-one innovation.⁵

Interested in more information on UC-II^® undenatured type II collagen?

*according to Frost & Sullivan, 2023

Lugo JP, Saiyed ZM, Lane NE. (2016). Efficacy and tolerability of an undenatured type II collagen supplement in modulating knee osteoarthritis symptoms: a multicenter randomized, double-blind, placebo-controlled study. Nutr J, 15(14). https://doi.org/10.1186/s12937-016-0130-8
Lugo et al. (2013). Undenatured type II collagen (UC-II®) for joint support: a randomized, double-blind, placebo-controlled study in healthy volunteers. J Int Soc Sports Nutr, 10(1), 48. https://doi.org/10.1186/1550-2783-10-48
Bagi CM, Berryman ER, Teo S, Lane NE. (2017). Oral administration of undenatured native chicken type II collagen (UC-II) diminished deterioration of articular cartilage in a rat model of osteoarthritis (OA). Osteoarthritis Cartilage, 25(12), 2080-2090. https://doi.org/10.1016/j.joca.2017.08.013
Yaremenko et al. (2021). Efficacy, tolerance and influence on cartilage metabolism of undenatured collagen type II UC-II (Mercana) in knee OA. PAIN, JOINTS, SPINE, 11(3), 5-12. doi: 616.718.56-001.056.
Juturu et al. (2021). Recovery of Undenatured Collagen Type II from Different Prototypes of Food and Beverages Using Enzyme-Linked Immunosorbent Assay (ELISA). Current Developments in Nutrition, 5(2), 327. https://doi.org/10.1093/cdn/nzab037_037

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. This information – including product information – is intended only for residents of the United States. The product discussed herein may have different labeling in different countries. All information on this website corresponds to Lonza’s knowledge on the subject at the date of publication. Republication of this information or related statements is prohibited. All trademarks belong to Lonza or its affiliates or with authorization from third-party owners of such trademarks and are used here only for informational purposes. Copyrighted material has been produced with permissions or under license, all other materials.